Precision Coating and Powder Layering Processes
The Granurex® precisely and consistently performs both coating and powder layering processes. In the pictures to the right, multiple coating and powder (ingredient) layers demonstrate the accuracy and control of a Granurex® rotor processor, including the creation of the nonpareil.
Unique, Efficient Granulation Processes
Granules produced by the Granurex® are dense and spherical in shape. The pictures and graphs shown below demonstrate how the Granurex® processes Ciprofloxacin from a 7µm poorly flowing powder to 200µm granules with excellent flow characteristics.
One Pot Processing
A patented feature of the Granurex® is its ability to dry product within the same processing chamber. This unique drying method, combined with 12 bar construction, provides a true one-pot system, ideal for manufacturing highly potent and expensive pharmaceutical compounds.
Increased Batch Capacities
The patented conical rotor plate increases batch capacities when compared to traditional rotor processors. The precision machined gap contains the product within the processing area and the peripheral spray guns are embedded into the product, which provides accurate coating with minimal spraying defects.
Maximum Process Flexibility
Using micronized acetaminophen as the base material, the Granurex® produced both a 100 µm granulation and a 200 µm spherical bead. In both of the examples below, the APAP core material had the same initial Mean Particle Size (X50) of 40 µm.
